Dr. Avinash G V
December 23, 2025 2025-12-23 8:00Dr. Avinash G V
B.Sc. Chemistry, Physics, & Mathematics (2008 to 2011) (69.7%)
University of Mysore, Bharathi College, Bharathi Nagara, Mandya District,
Karnataka, India.
M.Sc. Organic Chemistry (2011 to 2013) (CGPA 7.779/10)
University of Mysore, Mysore, Karnataka, India
Thesis:
“Synthesis and characterization of process impurity of Deferasirox”.
Ph.D. Medicinal Chemistry & Pharmacology (2017 to 2024)
(GPA 4.29/4.5)
University of Science and Technology
Korea Research Institute of Chemical Technology, South Korea.
Thesis:
“Part I- Discovery of PI4KIIIβ Inhibitors against Rhinovirus Replication”.
“Part II- Discovery of Non-Pyridinium Oxime Reactivators for
Organophosphate-Inhibited Acetylcholinesterase Reactivation”
Researcher
Korea Research Institute of Chemical Technology, Daejeon, South Korea.
Infectious Diseases Therapeutic Research Center (2019-2024)
Innovative Therapeutics Research Center (2017-2019)
Skills: Discovery of antiviral agents through HTS, Me-too approach and Structural Hybridization
Technique (SHT). Analyzing molecular docking study and X-ray crystal structure. Design and synthesis
of novel and complex molecules targeting rhinovirus, entrovirus, Zika and hepatitis B. Optimization of HIT
molecules for better pharmacological profiles. Synthesis of chiral compounds and highly unstable oxime
compounds acting as antidote for nerve agents. Collaboration with overseas universities and leading
pharmaceutical companies. Expert in interpretation of complex organic molecules using 1H NMR, 13C
NMR, LCMS, IR and GCMS. Expert in various chromatographic separation techniques like purifications
through prep HPLC, flash columns, prep plates and using instruments like isolera, combiflash and Grace.
❖ Research Associate II
Aurigene Discovery Technologies (A Dr. Reddy’s Company), Bengaluru, India.
Department of Medicinal Chemistry.
Skills: Familiar with modern methods of Organic synthesis and also capable of doing multi-step
synthesis. Expert in carrying out reactions at low temperature (-160°C) as well as at high temperatures
(250°C). Handled pyrophoric and explosive reagents like NaH, LAH, Pd/C, Raney Nickel, IBX, perchloric
acids, Diazomethane. Handled high pressure reactions using sealed tube and microwave.
❖ Research Associate I
Syngene International LTD (A Biocon Company) Bengaluru, India.
Department of Discovery Chemistry.
Skills: Expert in handling of moisture sensitive reagents such as BuLi, LDA, Grignard reagent, LiHMDS,
KHMDS, DiBAL-H, BH3.DMS. Palladium mediated coupling reactions like Suzuki coupling, Sonogashira
cross coupling, Buchwald coupling and Ulmann coupling. Proficient in both small-scale (10 mg) and largescale (500 gm) synthesis, with extensive experience in library synthesis.
- Highly potent and selective phosphatidylinositol 4-kinase IIIβ inhibitors as broad spectrum anti-rhinoviral
agents. Avinash G. Vishakantegowda; Dasom Hwang; Prashant Chakrasali; Eunhye Jung; Joo Youn
Lee; Jin Soo Shin; Young-Sik Jung. RSC Med. Chem., 2024, 15, 704–719.
https://doi.org/10.1039/D3MD00630A
2) Discovery of (E)-2-(Hydroxyimino)-N-(2 ((4methylpentyl)amino)ethyl)acetamide (KR-27425) as a nonpyridinium oxime reactivator of paraoxon-inhibited acetylcholinesterase. Avinash G. Vishakantegowda;
Solomon Girmay Berehe; Jin Soo Shin; Young-Sik Jung. Bioorganic & Medicinal Chemistry Letters, 2023,
96, 129504. https://doi.org/10.1016/j.bmcl.2023.129504.
3) Enteroviral replication inhibition by N-Alkyl triazolopyrimidinone derivatives through a non-capsid binding
3
Avinash G V Curriculum Vitae.docx – December 22, 2025
mode. Bishyajit Kumar Biswas; Jin Soo Shin; Yashwardhan R. Malpani; Dasom Hwang; Eunhye Jung;
Soo Bong Han; Avinash G. Vishakantegowda; Young-Sik Jung. Bioorganic & Medicinal Chemistry
Letters 2022, 4, 128673. https://doi.org/10.1016/j.bmcl.2022. 128673.
4) Sulfamoylbenzamide-based Capsid Assembly Modulators for Selective Inhibition of Hepatitis B Viral
Replication. Yeon Hee Lee; Hyeon-Min Cha; Jun Yeon Hwang; So Yeong Park; Avinash G.
Vishakantegowda; Ali Imran; Joo-Youn Lee; Yoon-Sun Yi; Sangmi Jun; Ga Hyeon Kim. ACS Med.
Chem. Lett. 2021, 12, 242–248. https://doi.org/10.1021/acsmedchemlett.0c00606.
5) Pyridinium-2-carbaldoximes with quinolinium carboxamide moiety are simultaneous reactivators of
acetylcholinesterase and butyrylcholinesterase inhibited by nerve agent surrogates. Hyun Myung Lee;
Rudolf Andrys; Jakub Jonczyk; Kyuneun Kim; Avinash G. Vishakantegowda; David Malinak; Adam
Skarka; Monika Schmidt; Michaela Vaskova; Kamil Latka. Journal of Enzyme Inhibition and Medicinal
Chemistry, 2021, 36, 437 449. https://doi.org/10.1080/14756366.2020.1869954.
Avinash G. Vishakantegowda; Joo-Youn Lee; Jin Soo Shin; Young-Sik Jung. Identification of NonQuaternary Oximes through HTS for Reactivation of Paraoxon Inhibited Acetylcholinesterase. Korean
Chemical Society (KCS) Meeting (2022), Jeju, South Korea.
2) Avinash G. Vishakantegowda; Prashant Chakrasali; Eunhye Jung; Young-Sik Jung. Design, Synthesis
and Evaluation of Broad-Spectrum Antiviral Activity of Aminothiazole Derivatives against Human
Rhinovirus and SARS-CoV-2. UST graduation presentation (2021), Daejeon, South Korea.
3) Avinash G. Vishakantegowda; Prashant Chakrasali; Chang-Soo Yun; Soo Bong Han; Young-Sik Jung.
Discovery of Novel Small Molecules for Inhibition of Rhinovirus Replication. Korean Chemical Society
(KCS) Medicinal Chemistry workshop (2019), South Korea.
