• • • Master of Science in Biochemistry. Department of Biochemistry, Manasagangothri, University of Mysore, Mysore, INDIA.    May/1999-2001
    • Ph. D. in Biotechnology. Department of Biotechnology, Manasagangothri, University of Mysore. Mysore, INDIA.   Jan/2002-2007
    • Bachelor of Science in Botany, Biochemistry, and Zoology (BBZ). Yuvaraj’s College, University of Mysore, Mysore, INDIA.  Feb/1996-1999

     

1. Lee C, Myung-Jin Kim M-J, Jung E, Zhang J, Kameshwar V H, Oh N, Kumar A. , Lee H-W,

Li X,  Kim Y. VEGF-B: A multifaceted modulator with emerging therapeutic applications.   Pharmacological Research. 2025 Dec. https://doi.org/10.1016/j.phrs.2025.108064. IF- 10.2

2. Ranjitha V R, Kumar A, Kaalappa P. Bionanoconjugates in Neurodegeneration: Peptide-Nanoparticle Alliances for Next-Generation Therapies. Pharm Res. 2025 Nov 6. doi: 10.1007/s11095-025-03941-0.                                                                                IF- 4.3
3. Praveenkumara J; Sanjay, M. R.;  Rangappa, Shobith;  C, Anilkumar; Prashantha, Kalappa; Siengchin, Suchart. Effect of infill pattern and filler ratio on the mechanical properties of 3D printed eco-friendly wollastonite/polylactic acid composites. Journal of Thermoplastic Composite Materials. 2025.                                                    IF- 3.6
4. Lee C, Kim M J, Kumar A, Lee H W, Yang Y, Kim Y. Vascular endothelial growth factor signaling in health and disease: from molecular mechanisms to therapeutic perspectives. Signal Transduct Target Ther. 2025 May 19;10(1):170. doi: 10.1038/s41392-025-02249-0.                                                                                                                             IF- 40.8
5. Lee C, Chen R, Sun G, Liu X, Lin X, He C, Xing L, Liu L, Jensen L, Kumar A, Langer H, Ren X, Zhang J, Huang L, Yin X, Kim J, Zhu J, Huang G, Li J, Lu W, Chen W, Liu J, Hu J, Sun Q, Lu W, Fang L, Wang S, Kuang H, Zhang Y, Tian G, Mi J, Bi-Ang Kang, Narazaki M, Prodeus A, Schoonjans L, Ornitz D, Gariepy J, Eelen G, Dewerchin M, Yang Y, JingSong Ou, Mora A, Yao J, Zhao C, Liu Y, Carmeliet P, Li X, and Cao Y. VEGF-B prevents excessive angiogenesis by inhibiting FGF2/FGFR1 pathway. Signal Transduct Target Ther. 2023 Aug 18;8(1):305. doi:10.1038/s41392-023-01539-9. IF- 40.8
6. Xing L, Huang G, Chen R, Huang L, Liu J, Ren X, Wang S, Kuang H, Kumar A, Kim JK, Qin Jiang Q, Li X and Lee C. Critical role of mitogen-inducible gene 6 in restraining endothelial cell permeability to maintain vascular homeostasis. J Cell Commun Signal. 2022 Oct 25. doi: 10.1007/s12079-022-00704                                                    IF- 4.5
7. Xiong Z, Wang Q, Li W, Huang L, Zhang J, Zhu J, Xie B, Wang S, Kuang H, Lin X, Lee C, Kumar A, Li X. Platelet-Derived Growth Factor-D Activates Complement System to Propagate Macrophage Polarization and Neovascularization. Front Cell Dev Biol. 2021 Jun 2;9:686886.                                                                                                    IF- 4.6
8. Liu L, Xing L, Chen R, Zhang J, Huang Y, Huang J, Xie B, Ren X, Wang S, Kuang H, Lin X, Kumar A, Kim JK, Lee C, Li X. Mitogen-Inducible Gene 6 Inhibits Angiogenesis by Binding to SHC1 and Suppressing Its Phosphorylation. Front Cell Dev Biol. 2021 Feb 22;9:634242.   IF- 4.6
9. Li X, Kumar A and Carmeliet P. Metabolic Pathways Fueling the Endothelial Cell Drive. Annu Rev Physiol. 2019 Feb 10; 81:483-503                                                        IF- 15.7
10. Arjunan P, Lin X, Tang Z, Du Y, Kumar A, Liu L, Yin X, Huang L, Chen W, Chen Q, Ye Z, Wang S, Kuang H, Zhou L, Xu K, Chen X, Zeng H, Lu W, Cao Y, Liu Y, Zhao C, Li X. VEGF-B is a potent antioxidant. Proc Natl Acad Sci U S A. 2018 Oct 9;115(41):10351-10356. IF- 9.4
11. Kumar A and Li X. PDGF-C and PDGF-D in ocular diseases. Mol Aspects Med. 2018 Aug; 62: 33-43. IF- 8.7
12. Xu H, Zhang L, Chen W, Xu J, Zhang R, Liu R, Zhou L, Hu W, Ju R, Lee C, Lu W, Kumar A, Li X and Tang Z. Inhibitory Effect of Caveolin-1 in Vascular Endothelial Cells, Pericytes and Smooth Muscle Cells. 2017                IF- 3.76
13. Huang D, Zhao C, Ju R, Kumar A, Tian G, Huang L, Zheng L, Li X, Liu L, Wang S, Ren X, Ye Z, Chen W, Xing L, Chen Q, Gao Z, Mi J, Tang Z, Wang B, Zhang S, Lee C, Li X. VEGF-B inhibits hyperglycemia and Macugen induced retinal apoptosis. Sci Rep. 2016: May 18;6:26059. IF- 3.8
14. Rebecca I. S, Frank R, Peter K, Kumar A, Mario L, Franziska T, Kerstin G, Tobias G, Axel B, Sebastian W, Lorraine O’R, Sven G. M, Klaus Schulze-O, Meinrad G, Li X, Christoph K, Frank E, Harald F. L. Platelets induce apoptosis via membrane-bound FasL. 2015: Sep 17;126 (12):1483-1493. IF- 21.0
15. He C, Zhao C, Kumar A, Lee C, Chen M, Huang L, Wang J, Chen W, Wang B, Gao Z, Zhong Z, Zhang F, Huang B, Ding H, Ju R, Tang Z, Liu Y, Cao Y, Li X. Vasoprotective effect of PDGFCC mediated by HMOX1 rescues retinal degeneration. Proc Natl Acad Sci USA,14806– 14811,doi: 10.1073/pnas.140414011, 2014                              IF- 9.4
16. Kumar A, Zhao L, Paul G M, Fariss R N, Wong W T. Vascular associations and dynamic process motility in perivascular myeloid cells of the mouse choroid: implications for function and senescent change.IOVS 55 (3), 1787–1796. 2014.      IF- 5.0                                               
17. Condren A B , Kumar A, Mettu P, Liang K J, Zhao L, Jen-yue Tsai, Fariss R N, Wong W T. Perivascular Mural Cells of the Mouse Choroid Demonstrate Morphological Diversity That Is Correlated to Vasoregulatory Function. PLoS One.;8(1):e53386. doi: 10.1371/ pone. 0053386. 2013.                                  IF- 2.94
18. Segarra M, Ohnuki H, Maric D, Salvucci O, Hou X, Kumar A, Li X, Tosato G. Semaphorin 6A regulates angiogenesis by modulating VEGF signaling. September 24, 2012.                                                                     IF- 21.0
19. Zhang F, Li Y, Kumar A, Tang Z, Lee C, Ma W, Langer H, Zhang L, Jensen L, Arjunan P, Strasser A, Wong W, Chavakis T, Cao Y, Li X. Proliferative and survival effects of PUMA promotes angiogenesis. Cell Reports, September 2012.                                              IF- 7.50
20. Li X, Kumar A, Zhang F, Lee C, Tang    Complicated life complicated VEGF-B. Trends  Mol. Med. Feb 2012.                                                                                                       IF- 12.80
21. Lee C, Tang Z, Li Y, Arjunan P, Hou X, Zhang F. Can VEGF-B be used to treat neurodegenerative diseases? Neurodegenerative Diseases. ISBN: 978-953-307-485-6 (Book chapter) Intech publication, 2011.
22. Tang Z, Zhang F, Li Y, Arjunan P, Kumar A, Lee C, Li X. A mouse model of the cornea pocket assay for angiogenesis study. J Vis Exp. Aug 18; 54, 2011. Video journal.  IF- 1.70
23. Tang Z, Zhang S, Lee C, Kumar A, Arjunan P, Li Y, Zhang F, Li X. An optic nerve crush injury murine model to study retinal ganglion cell survival. J Vis Exp. Apr 25; 50, 2011. Video journal                                                    IF- 1.70
24. Li X, Kumar A, Zhang F, Lee C, Li Y, Tang Z, Arjunan P. VEGF-independent angiogenic pathways induced by PDGF-C. 1(4):309-314, 2010.                              IF- 3.76
25. Kumar A, Hou X, Li Y, Lee C, Maminishkis A, Tang Z, Zhang F, Arjunan P, Dong L, Wu Z, Zhu LY, Dong L, Colosi P, Li X. PDGF-DD targeting arrests pathological angiogenesis by modulating GSK3β phosphorylation. J Biol Chem. 285(20):15500- 15510, 2010.IF- 4.0
26. Hou X, Kumar A, Lee C, Wang B, Arjunan P, Maminishkis A, Dong L, Tang Z, Li Y, Zhang F, Zhang S-H, Wang F, Wardega F, Wu Z, Fariss RN, Colosi P, Gutkind S, Cao Y, Lennartsson J, Li X. PDGF-CC blockade inhibits pathological angiogenesis by acting on multiple cellular and molecular targets. Proc Natl Acad Sci USA. 107(27):12216- 12221, 2010.                                                                                                                                     IF- 9.4
27. Tang Z, Arjunan P, Lee C, Li Y, Kumar A, Hou X, Wang B, Wardega P, Zhang F, Dong L, Zhang Y, Zhang S Z, Ding H, Fariss R, Becker K G, Lennartsson J, Nagai N, Cao Y, Li X. Survival effect of PDGF-CC rescues neurons from apoptosis in both brain and retina by regulating GSK3beta phosphorylation. J Exp Med, 207(4):867-880, 2010.                                                                                                                          IF- 15.30
28. Zhang F, Tang Z, Hou X, Lennartsson J, Li Y, Koch AW, Scotney P, Lee C, Arjunan P, Dong L, Kumar A, Rissanen TT, Wang B, Nagai N, Fons P, Fariss R, Zhang Y, Wawrousek E, Tansey G, Raber J, Fong GH, Ding H, Greenberg DA, Becker KG, Herbert JM, Nash A, Yla-Herttuala S, Cao Y, Watts RJ, Li X. VEGF-B is dispensable for blood vessel growth but critical for their survival, and VEGF-B targeting inhibits pathological angiogenesis. Proc Natl Acad Sci Apr 14; 106(15):6152- 6157, 2009. IF- 9.4
29. Xuri Li, Chunsik Lee, Zhongshu Tang, Fan Zhang, Pachiappan Arjunan, Yang Li, Xu Hou, Anil Kumar and Lijin Dong. VEGF-B A survival or an angiogenic factor? Cell Adh Migr. Oct-Dec 2009; 3(4):322-7.             IF- 3.30
30. Anil Kumar. C, Nanjunda Swamy. S, Gaonkar^. L, Basappa, Bharathi. P Salimath and Kanchugarakoppal S Rangappa. “N- substituted-2-butyl-5-chloro-3H- imidazole-4carbaldehyde derivatives as anti-tumor agents against Ehrlich ascites tumor cells in vivo”. Medicinal Chemistry, 03, 269-276, 2007.                                              IF- 1.90
31. Anil Kumar. C, Basappa, Bharathi. P Salimath and Kanchugarakoppal S Rangappa. “Proapoptotic activity of N- substituted-2-butyl-5-chloro-3H-imidazole-4- carbaldehyde derivatives mediated by activation of caspase activated DNase. Investigational New Drugs, ; 25,343-350, 2007.                                                                                            IF- 3.0

Priya B.S., Anil Kumar C., Nanjunda Swamy S., Basappa, Naveen S., Shashidhara Prasad J and Rangappa K.S. “2-(2-(2-Ethoxybenzoylamino) -4- chlorophenoxy) -N- (2ethoxybenzoyl) benzamine inhibits EAT cell induced angiogenesis by down regulation of VEGF secretion”. Bioorganic & Medicinal Chemistry Letters, 17, 10, 2775-2780,

1. 1. Advances in sustainable chemical science and technology: Workshop sponsored by Royal Society of Chemistry. 11^th – 12^th December 2025 @ Global Broadcasting Centre – organised by CRI and ASNS. Session Chair.
   2. Current trends in drug discovery techniques and diagnostics: Chemical Biology approaches. 2^nd & 3^rd Aug, 2024 @ ACU. G. Nagara, Mandya, India.

   Convener – International Conference

   1. Sphingosine kinase-1 mediates the migration of retinal pigment epithelial cells and inflammation in subretinal matrigel-induced CNV. Harshith J M, Qianqian Wang, Xiong Zhen, Xuri Li, Prashantha Kalappa, Shobith Rangappa and Anil Kumar. 11^th CBS(I) Annual meeting on current trends in drug discovery techniques and Diagnostics: Chemical biology approaches.  02^nd – 03^rd, Aug 2024, in ACU, B. G. Nagara, Mandya, India.

   Poster presentation.

   1. PDGF-D instigated complement activation promoted neuro-retinal inflammation. Anil Kumar, Zhen Xiong, Wanhong Li and Xuri Li. Association for Research in Vision and Ophthalmology (ARVO) Annual Meeting, April 28 – May 05, 2019 in Vancouver, Canada. Poster presentation.
   2. Sphingosine kinase -1 mediates retinal epithelial cell migration and inflammation in subretinal matrigel-induced CNV. Qianqian Wang, Xiong Zhen, Wanhong Li, Xuri Li and Anil Kumar. Asia Pacific Vascular Biology Organization (APVBO) May 09-12, 2019, International conference at Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China. Poster presentation.  
   3. Role of Sphingosine Kinase-1 in Retinal pigment epithelial cell migration. Anil Kumar,

   Qianqian Wang, Xiong Zhen, Wanhong Li and Xuri Li. Association for Research in

   Vision and Ophthalmology (ARVO) 2018  Annual Meeting, April 29 – May 03, 2018, in Honolulu, Hawaii. Poster presentation.

   1. Participated in the PDGF symposium May 14-15, 2018, at the University of Louvain- UCL Brussels, Belgium.
   2. Association between choroidal macrophages and perivascular mural cells and their influence in choroidal pathology. Anil Kumar, Zhen Xiong, Wanhong Li and Xuri Li. 20th International Vascular Biology Meeting (IVBM2018), June 3-7, 2018, in Helsinki, Finland Poster presentation.
   3. Effect of complement system in PDGF-D induced neurovascular inflammation. Asia Pacific Vascular Biology Organization (APVBO 2017), November 17-20, 2017, International conference at Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.  
   4. Organized and participated in the China Vascular Biology Organization (CVBO) Symposium at the June 25, 2017, conference, Zhongshan Ophthalmic Center at Sun Yat-sen University, Guangzhou, China.
   5. Interaction between resident macrophages and perivascular mural cells of the choroid: Relevance to pathological choroidal changes in retinal disease. Anil Kumar, Lian Zhao, Robert N. Fariss & Wai T. Wong. ARVO Annual Meeting, Leading Eye and Vision Research, May 4 – 8, 2014. Orlando, Florida. Poster presentation
   6. Resident myeloid cells in the mouse choroid show diverse associations with choroidal vessels and display prominent dynamic process motility. Anil Kumar, Lian Zhao, Robert N. Fariss & Wai T. Wong. Focus on fellows-2013, NEI/NIH. Maryland, USA. Oral presentation.
   7. Distribution, morphology, and dynamic behaviour of macrophages in the adult mouse choroid. Anil Kumar, Lian Zhao, Robert N. Fariss & Wai T. Wong. ARVO Annual Meeting, Life-Changing Research, May 5-9, 2013, in Seattle, Washington. Poster presentation.
   8. Proapoptotic and Antiangiogenic activity of imidazole derivatives mediated by upregulation of Bax and down regulation of VEGF. Rangappa K. S., Anil Kumar C., Bharathi P. Salimath. Benzon symposium, No-54, Glycosylation opportunities in drug development. June 11-14, 2007. Copenhagen, Denmark. Poster Presentation. 
   9. Participated in the “92nd Indian Science Congress” held in Ahmedabad, Gujarat. INDIA. January 3-7, 2005.
   10. Synthesis of substituted imidazole analogues as new antiangiogenic agents. K. S. Rangappa, Basappa, Anil Kumar C. Bharathi P. Salimath. IUPAC international conference. New Delhi, INDIA. January 2004, 26-31. Poster presentation.
   11. Substituted Imidazole analogs as novel antiangiogenic agents. Anil Kumar C, Basappa, Rangappa K. S., Bharathi P. Salimath. 3^rd National Symposium on Venoms and Toxins held in the Department of Biochemistry, Mansagangothri, Mysore. January 23-26, 2004. Poster presentation.

• Research fellow at Unit on Neuron-Glia Interactions in Retinal Disease (UNGIRD) from 2013-2015, National Eye Institute, National Institutes of Health (NIH), Maryland, USA.
• The O-1 visa, sponsored by the NIH, is exclusively available to individuals with extraordinary talent (2013-2015).
• Postdoctoral visiting fellow at the Unit on Neuron-Glia Interactions in Retinal Disease (UNGIRD) from 2012-2013, National Eye Institute, NIH, Maryland, USA.
• Merit award from NEI/NIH, April 23, 2010.
• Postdoctoral visiting fellow at the Unit on Retinal Vascular Neurobiology (URNV) from 2008- 2012, National Eye Institute, NIH, Maryland, USA.
• DBT- Junior Research fellow 2003-2006 Department of Biotechnology, University of Mysore, INDIA.

•  

  1. Research grants from Zhongshan Ophthalmic Center, Sun Yet-Sun University, Guangzhou, China.

•  

  Sl no	Project	Research Funding No	Funds awarded	Funds in Rupees
  1	2016 Research start-up fund	3030901010102	RMB 500,000	59 lakhs
  2	2017 PI-Research funding	3030902113138	RMB 200,000	24 lakhs
  3	2018 PI-Research funding	3030902113069	RMB 200,000	24 lakhs
  4	2019 PI-Research funding	303010303062	RMB 200,000	24 lakhs
  5	2020 PI-Research funding	303011303065	RMB 250,000	29 lakhs
  Total			1.35 million RMB	1.60 Crore

   

  Sl	Project title	PI/Co-PI	Year	Funding agency	Amount applied	Ongoing / completed
  1	Harnessing sericin and sericin-derived peptides for ocular therapeutics: Novel strategies to combat ECM degradation and angiogenesis in AMD.	PI	2025	CSB	70 lakhs	Applied
  2	From Fenugreek Seeds to Sight: Uncovering the Retinoprotective Potential of 4-Hydroxyisoleucine.	PI	2025	ANRF-ARG	106 lakhs	Applied
  3	Liposome-encapsulated nanoselenium-peptide complexes for precise glioblastoma treatment and neuroprotection.	Co-PI	2025	ANRF-ARG	77 lakhs	Applied
  4	Enhanced Neuroprotective Delivery: Synergistic Short Peptide Selenium Nanocomplexes Encapsulated in Nanostructured Lipid Carriers.	Co-PI	2025	DST-SYST	50 lakhs	Applied

  Ph.D. students enrolled – 05.

  Ph.D. students with a degree awarded – 02.

  Postdoctoral students – 02.  

  PG students for dissertation – 18

• Five-week hands-on training programme on “Fundamental Techniques in Modern Biology”, sponsored by the Department of Health Research, Ministry of Health and Family Welfare, Government of India (ICMR–DHR), and jointly organized by the Centre for Molecular and Nanomedical Sciences, Sathyabama Institute of Science and Technology, Chennai, held from 12 November 2025 to 20 December 2025.

• Two-day International Conference on “New Challenges and Innovations in Molecular Medicine” (NCIMM-2025), organized by the Department of Studies in Chemistry and the Department of Studies in Organic Chemistry, University of Mysore (UoM), held on 27–28 May 2025.