MS: in Chemistry, Western Illinois University, IL, USA,

M.Sc.: in Biotechnology, Bangalore University, KA, India

• 1. Phytochemicals specifically dietary sources and their characterization.
  2. Organic synthesis of new chemical entities as therapeutic agents.

  3. Research interests include phenoxazine-based Akt inhibitor development, plant phytochemical extraction and assessment, microbiological evaluation of bioactive compounds, and in vivo efficacy and toxicity studies.

• 1. Sl	Principle Investigator	Co-Principle Investigator	Project Title	Funding Agency	Year of Sanction	Duration of Project	Status	Amount in Lakhs
     1	Parimala Hanumesh	N/A	Synthesis, characterization and preliminary screening of N10– substituted phenoxazines libraries.	ACU	2020	3yrs	On-Going	1.5 lakh
     2	Dr. Naga Prashant K	Parimala Hanumesh	Design, Molecular modelling and evaluation of novel neuro-protective therapeutics-scheme development of peptide candidates as BACE 1 Inhibitors for Alzheimer disease-SPS Approach	ACU	2025		On-Going	2.75

1. Thammanna Gowda SS *, Parimala B Hanumesh and Manjula RVAntimicrobial activity of Punica grantum leaves. International Journal of Science and Research Archive, 2021,03(02), 214–217. doi.org/10.30574/ijsra.2021.3.2.0162
2. Brandon M. Young, Janice L. Hyatt, David C. Bouck †,Taosheng Chen, Parimala Hanumesh, Jeanine Price, Vincent A. Boyd, Philip M. Potter, and Thomas R. Webb: Structure−Activity Relationships of Substituted 1-Pyridyl-2-phenyl-1,2- ethanediones: Potent, Selective Carboxylesterase Inhibitors. J. Med. Chem., 2010, 53 (24), pp 8709–8715. doi.org/10.1021/jm101101q
3. P. Jake Slavish, Jeanine E. Price, Parimala Hanumesh, and Thomas R. Webb: Efficient Synthesis of Pyrazolopyrimidine Libraries, J. Comb. Chem., 2010, 12 (6), pp 807–809. doi.org/10.1021/cc1001204
4. Vincent A. Boyd, John Mason, Parimala Hanumesh, Jeanine Price: 2-substituted- 4,5-Dihydroxypyrimidine-6-Carboxamide Antiviral Targeted Libraries. J. Comb. Chem., 2009, 11 (6), pp 1100–1104. DOI: 10.1021/cc900111u
5. Mayur MC, Padma T, Parimala BH, Chandramouli KH, Jagadeesh S,Gowda NM, Thimmaiah KN: Sensitization of multidrug resistant (MDR) cancer cells to vinblastine by novel acridones: correlation between anti-calmodulin activity and anti- MDR activity, J. Med Chem., 2 (1), 63-77, 2006. DOI: 10.2174/157340606775197732
6. Jagadeesh S, Padma T, Parimala BH, Chandramouli KH, D’Souza CJ, Thimmaiah KN: Inhibition of calmodulin-dependent cyclic AMP phosphodiesterase by phenoxazines, Biochem. Biophys Res Commun., 342 (3), 690-701, 2006. DOI: 10.1016/j.bbrc.2006.01.183

7. Hanumesh, Parimala, Ravi Mundugaru, K. Amita, K. Prashantha, and Shobith Rangappa.
   Biological assessment of 3-phenylpropyl acetate as a wound healing agent.
   Journal of Biologically Active Products from Nature (2025): 1–9.
   https://doi.org/10.1080/22311866.2025.2570156

8. Priyadarshini, H. N., Parimala Hanumesh, V. Pavitra, Mohd Shkir, K. H. Kumar, S. Appu, B. R. Anusha et al.
   Visible light active Fe2O3/TiO2 nanocomposite for enhanced photocatalytic activity and nitrite sensing efficiency.
   Topics in Catalysis (2025): 1–18.
   https://doi.org/10.1007/s11244-025-02145-5

9. SS, Thammanna Gowda, Shobith Rangappa, and Parimala Hanumesh.
   The Impact of Epigenetic Factors in Type 2 Diabetes: Insights into Development and Pathogenesis.
   Obesity Medicine (2025): 100635.
   https://doi.org/10.1016/j.obmed.2025.100635

10. Thammannagowda, Vishnu Kadabahalli, Kariyappa Gowda Guddenahalli Shivanna, Ajeya Keresanthe Parameshwarappa, Parimala Hanumesh, and Prashantha Kalappa.
    Photocatalytic degradation of methylene blue using CoFe2O4/Ag2WO4: Efficiency in degradation of methylene blue dye removal and antimicrobial activity.
    Next Materials 8 (2025): 100774.
    https://doi.org/10.1016/j.nxmate.2025.100774

11. Shivanna, Kariyappa Gowda Guddenahalli, Vishnu Kadabahalli Thammannagowda, Parimala Hanumesh, and Prashantha Kalappa.
    Multifunctional hydrothermally synthesized MgFe2O4–Ag2WO4 nanocomposite for enhanced photocatalytic and antibacterial applications.
    Chemical Physics Letters (2025): 142265.
    https://doi.org/10.1016/j.cplett.2025.142265

12. Hanumesh, Parimala, and Shobith Rangappa.
    An Overview of 3-Phenylpropyl Acetate: A Multifaceted Fragrance and Flavouring Compound.
    Flavour and Fragrance Journal 40, no. 2 (2025): 183–189.
    https://doi.org/10.1002/ffj.3839

13. Lokesh Ravilla, Parimala Hanumesh, Thammanna Gowda SS, Manjunath V. Shinnur, Ajay Prabu B, Jayapraksh G, Sourabh S.H., and Shobith Rangappa.
    Efficient method for the synthesis of prilocaine precursor amide using 2-chloropropanoic acid by skipping the use of thionyl chloride.
    Int. J. Chem. Biol. Sci., 2024; 6(1): 38–42.
    https://doi.org/10.33545/26646765.2024.v6.i1a.78

14. Young, Brandon M., Janice L. Hyatt, David C. Bouck, Taosheng Chen, Parimala Hanumesh, Jeanine Price, Vincent A. Boyd, Philip M. Potter, and Thomas R. Webb.
    Structure–Activity Relationships of Substituted 1-Pyridyl-2-phenyl-1,2-ethanediones: Potent, Selective Carboxylesterase Inhibitors.
    Journal of Medicinal Chemistry 53, no. 24 (2010): 8709–8715.
    https://doi.org/10.1021/jm101101q

15. Slavish, P. Jake, Jeanine E. Price, Parimala Hanumesh, and Thomas R. Webb.
    Efficient synthesis of pyrazolopyrimidine libraries.
    Journal of Combinatorial Chemistry 12, no. 6 (2010): 807–809.
    https://doi.org/10.1021/cc1001204

16. Vincent A. Boyd, John Mason, Parimala Hanumesh, Jeanine Price.
    2-substituted-4,5-Dihydroxypyrimidine-6-Carboxamide Antiviral Targeted Libraries.
    J. Comb. Chem., 2009, 11(6), 1100–1104.
    https://doi.org/10.1021/cc900111u

17. Jagadeesh, Shankar, Thimmaiah Padma, Hanumesh Parimala, K. H. Chandramouli, Cletus J.M. D’Souza, and Kuntebommanahalli N. Thimmaiah.
    Inhibition of calmodulin-dependent cyclic AMP phosphodiesterase by phenoxazines.
    Biochemical and Biophysical Research Communications 342, no. 3 (2006): 690–701.
    https://doi.org/10.1016/j.bbrc.2006.01.183

18.  

• Piperidine ureas as cathepsin cysteine protease inhibitors No.WO2016027284A3